Over-the-Counter Anxiety Remedies You Can Use Right Now

Feeling jittery and want something you can pick up at the pharmacy? You don’t need a prescription for every anxiety fix. Below are the most common OTC options that actually help calm nerves without a doctor’s note.

What Works Without a Script

Diphenhydramine (Benadryl) – The old‑school antihistamine doubles as a mild sedative. One 25 mg tablet at night can ease racing thoughts, but avoid daytime use because it can make you drowsy.

Magnesium supplements – Low magnesium is linked to nervous tension. A 200‑400 mg magnesium glycinate or citrate taken with food can smooth out muscle twitches and quiet the mind.

L‑theanine – This amino acid from tea promotes alpha‑wave activity, giving a relaxed focus. A 100‑200 mg dose works well before work or a meeting.

Valerian root capsules – Valerian has been used for centuries to settle anxiety. One 400‑600 mg capsule about an hour before bedtime can help you unwind.

Passionflower tablets or tincture – Passionflower may lower cortisol spikes. A typical dose is 250 mg of dried extract or 20‑30 drops of tincture, taken twice daily.

Herbal and Lifestyle Helpers

Beyond pills, simple things like chamomile tea, lavender essential oil, or a short walk can cut stress. These aren’t “medicines,” but they pair nicely with the OTC options above.

When you try any new product, start with the lowest dose. Watch how your body reacts for a few days before you increase the amount. If you notice excessive drowsiness, dry mouth, or a racing heart, stop and switch to a different remedy.

Keeping a quick symptom journal helps you see which option actually eases your anxiety. Jot down the time you take the product, how you feel after 30 minutes, and any side effects.

Remember, OTC remedies are for mild to moderate anxiety. If worries keep you up for nights on end, or you notice panic attacks, it’s time to talk to a healthcare professional.

Most pharmacies also carry combination products like “Sleep Easy” bundles that mix diphenhydramine with melatonin. These can be a handy one‑stop for bedtime anxiety, but read the label to avoid double‑dosing on sleep aids.

Finally, watch the expiration dates. Some herbal extracts lose potency after a year, and stale supplements can irritate your stomach.

With these easy‑to‑find options, you can tackle everyday nerves without navigating a prescription maze. Pick one that fits your lifestyle, start low, and give your body a few days to adjust. You’ll likely notice a calmer mood and clearer thoughts in no time.

Benadryl for Anxiety: Real Reasons Doctors Advise Against It and Safer OTC Alternatives
By Celia Rawdon
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