Cefpodoxime Dosage: What You Need to Know

If you’ve been prescribed cefpodoxime, the biggest question is probably "how much should I take?" The answer isn’t one‑size‑fits‑all – it changes with age, the infection you’re fighting, and how well your kidneys work. Below you’ll find the most common dosing schedules, the tweaks you might need, and simple tips to keep the treatment effective and safe.

Standard Doses for Adults and Kids

For most adults, the typical oral dose is 200 mg every 12 hours, taken with or without food. Some infections, like uncomplicated urinary‑tract infections, may be treated with 400 mg once a day. The total daily amount usually stays between 200 mg and 400 mg, depending on the bug and how severe the infection is.

Kids get a weight‑based dose. The usual recommendation is 8 mg per kilogram of body weight every 12 hours. For example, a 30‑kg child would take about 240 mg twice daily. The medication comes in 100 mg tablets and a liquid suspension (usually 100 mg/5 ml), so you can measure the exact amount you need.

Treatment length also matters. Most doctors prescribe cefpodoxime for 5 to 10 days. Shorter courses (5 days) work well for simple ear or sinus infections, while deeper infections like pneumonia may need a full 10 days.

Adjusting the Dose for Special Situations

If you have reduced kidney function, the drug stays in your system longer, so the dose must be lowered. For a creatinine clearance below 30 ml/min, doctors often cut the dose in half – that means 100 mg every 12 hours for adults, or 4 mg/kg for kids.

People with liver disease usually don’t need a change because cefpodoxime is cleared primarily by the kidneys. However, always tell your doctor about any liver issues just in case.

Missed a dose? Take it as soon as you remember unless it’s almost time for the next one. Don’t double up – a double dose can increase side‑effects without improving the infection fight.

Common side effects include mild stomach upset, diarrhea, and a occasional rash. If you notice severe diarrhea (especially watery or bloody), fever, or signs of an allergic reaction (hives, swelling, breathing trouble), call your doctor right away.

Finally, store the liquid suspension in the refrigerator and shake it well before each use. Tablets should be kept in a dry place away from heat.

Bottom line: follow the exact dose your prescriber gave you, adjust for weight or kidney health, finish the full course, and watch for any unusual reactions. When you stick to these basics, cefpodoxime does a solid job clearing up bacterial infections without causing unnecessary trouble.

Cefpodoxime for Dogs and Cats: Veterinary Uses, Dosage, and Precautions
By Celia Rawdon
Cefpodoxime for Dogs and Cats: Veterinary Uses, Dosage, and Precautions

Get a detailed guide on cefpodoxime in veterinary medicine: how it's used for dogs and cats, correct dosing, side effects, real pet care tips, and what to avoid.